Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) technology combines the advantages of Time-Resolved Fluorescence (TRF) and Fluorescence Resonance Energy Transfer (FRET). By utilizing the long fluorescence lifetime and high stability of lanthanide elements, TR-FRET offers an experimental approach that is easy to use, homogeneous (no washing required), stable, with lower background, improved signal-to-noise ratio, and greater sensitivity.