Shanghai VKEY Biotechnologies Co.,Ltd.
Shanghai VKEY Biotechnologies Co.,Ltd.
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Epigenetic

Epigenetic enzymes are indispensable to the process of epigenetic modification. DNA methyltransferases can add methyl groups to cytosine residues in specific regions of DNA. 

This process regulates gene expression and affects cell differentiation, development and disease development. Histone - modifying enzymes are responsible for various modifications of histones, such as acetylation, methylation, phosphorylation, etc. 

These modifications will change the structure and function of chromatin, leaving it in an open or closed state, and then affect the accessibility and transcriptional activity of genes, playing a crucial regulatory function in various physiological and pathological processes.

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KeyTec® KAT6B, N-His-Flag
KeyTec® KAT6B, N-His-Flag
Species: Human; Expression Host: E.coli; Tag: N-terminal His-Flag; Sequence: R718-A1008; Purity: SDS-PAGE
CAT. / P2HE0022S / P2HE0022L
KeyTec® KAT8(MYST1), N-His-Flag
KeyTec® KAT8(MYST1), N-His-Flag
Species: Human; Expression Host: Insect(Sf9); Tag: N-terminal His-Flag; Sequence: M1-K458(end); Purity: SDS-PAGE; Application: TR-FRET; Activity: Enzyme activity
CAT. / P2HI0024S / P2HI0024L
KeyTec® METTL3/METTL14, N-Flag/N-His
KeyTec® METTL3/METTL14, N-Flag/N-His
Species: Human; Expression Host: Insect(Sf9); Tag: N-terminal Flag/N-terminal His; Sequence: S2-L580/D2-R456; Purity: SDS-PAGE
CAT. / P2HI0025S / P2HI0025L
KeyTec® NSD1, N-GST
KeyTec® NSD1, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: K1849-E2094; Purity: SDS-PAGE
CAT. / P2HE0026S / P2HE0026L
KeyTec® NSD2, N-GST
KeyTec® NSD2, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: E941-D1240; Purity: SDS-PAGE
CAT. / P2HE0027S / P2HE0027L
KeyTec® NSD3, N-GST
KeyTec® NSD3, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: E1021-H1320; Purity: SDS-PAGE
CAT. / P2HE0028S / P2HE0028L
KeyTec® PRMT3, N-His
KeyTec® PRMT3, N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: C2-Q531(end); Purity: SDS-PAGE
CAT. / P2HE0029S / P2HE0029L
KeyTec® SETD2, N-GST
KeyTec® SETD2, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: D1418-S1714 ; Purity: SDS-PAGE
CAT. / P2HE0030S / P2HE0030L
KeyTec® SIRT2, C-His
KeyTec® SIRT2, C-His
Species: Human; Expression Host: E.coli; Tag: C-terminal His; Sequence: S50-S356; Purity: SDS-PAGE
CAT. / P2HE0031S / P2HE0031L
KeyTec® SIRT3, N-GST
KeyTec® SIRT3, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: I102-K399(end); Purity: SDS-PAGE
CAT. / P2HE0032S / P2HE0032L
KeyTec® SIRT5, N-GST
KeyTec® SIRT5, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: M1-S310(end); Purity: SDS-PAGE
CAT. / P2HE0033S / P2HE0033L
KeyTec® SIRT6, N-GST
KeyTec® SIRT6, N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: M1-S355(end); Purity: SDS-PAGE
CAT. / P2HE0034S / P2HE0034L
KeyTec® SMARCAL1, N-His; C-Avi
KeyTec® SMARCAL1, N-His; C-Avi
Species: Human; Expression Host: Insect(Sf9); Tag: N-terminal His; C-terminal Avi; Sequence: S2-L594(end); Purity: SDS-PAGE
CAT. / P2HI0037S / P2HI0037L
KeyTec® SMYD2, N-His
KeyTec® SMYD2, N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: R2-H433(end); Purity: SDS-PAGE
CAT. / P2HE0038S / P2HE0038L
KeyTec® BRD2 (BD1/BD2), N-His
KeyTec® BRD2 (BD1/BD2), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: E65-E459; Purity: SDS-PAGE
CAT. / P2HE0048S / P2HE0048L
KeyTec® BRD2(BD1), N-His
KeyTec® BRD2(BD1), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: E65-L187; Purity: SDS-PAGE
CAT. / P2HE0042S / P2HE0042L

Outstanding Features

Strict Quality Control
Strict Quality Control

A strict QC (quality control) test report is provided for each batch.

Good Enzyme Activity
Good Enzyme Activity

Each batch has been verified for enzyme activity. 

Suitable for High-Throughput Screening
Suitable for High-Throughput Screening

Verified by common homogeneous methods such as TR-FRET, Luminescence and fluorescence. 

Cost-Effective
Cost-Effective

High-performance at competitive prices.

Product Competitiveness

Product Competitiveness

For KeyTec® protein products, each batch of protein is subjected to a series of rigorous validation procedures to obtain data such as purity, monomer/polymer morphology, enzyme activity information, positive compound validation information, and so forth.