Shanghai VKEY Biotechnologies Co.,Ltd.
Shanghai VKEY Biotechnologies Co.,Ltd.
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Epigenetic

Epigenetic enzymes are indispensable to the process of epigenetic modification. DNA methyltransferases can add methyl groups to cytosine residues in specific regions of DNA. 

This process regulates gene expression and affects cell differentiation, development and disease development. Histone - modifying enzymes are responsible for various modifications of histones, such as acetylation, methylation, phosphorylation, etc. 

These modifications will change the structure and function of chromatin, leaving it in an open or closed state, and then affect the accessibility and transcriptional activity of genes, playing a crucial regulatory function in various physiological and pathological processes.

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KeyTec® BRD2(BD2), N-His
KeyTec® BRD2(BD2), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: N339-E459; Purity: SDS-PAGE
CAT. / P2HE0043S / P2HE0043L
KeyTec® BRD3 (BD1/BD2), N-His
KeyTec® BRD3 (BD1/BD2), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: P29-D417; Purity: SDS-PAGE
CAT. / P2HE0047S / P2HE0047L
KeyTec® BRD3(BD1), N-His
KeyTec® BRD3(BD1), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: P29-V145; Purity: SDS-PAGE
CAT. / P2HE0044S / P2HE0044L
KeyTec® BRD3(BD2), N-His
KeyTec® BRD3(BD2), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: G306–D417; Purity: SDS-PAGE
CAT. / P2HE0052S / P2HE0052L
KeyTec® BRD4 (BD1/BD2), N-His
KeyTec® BRD4 (BD1/BD2), N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: E49-E460(end); Purity: SDS-PAGE
CAT. / P2HE0040S / P2HE0040L
KeyTec® BRD9, N-His
KeyTec® BRD9, N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: N135-A242; Purity: SDS-PAGE
CAT. / P2HE0045S / P2HE0045L
KeyTec® BRDT(BD1/BD2), N-GST
KeyTec® BRDT(BD1/BD2), N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST; Sequence: T22–E382; Purity: SDS-PAGE
CAT. / P2HE0046S / P2HE0046L
KeyTec® HDAC1, C-Flag-His
KeyTec® HDAC1, C-Flag-His
Species: Human; Expression Host: Insect(Sf9); Tag: C-terminal Flag-His; Sequence: M1-A482(end); Purity: SDS-PAGE
CAT. / P2HI0050S / P2HI0050L
KeyTec® HDAC4, C-GST
KeyTec® HDAC4, C-GST
Species: Human; Expression Host: Insect(Sf9); Tag: C-terminal GST; Sequence: S101-L1084(end); Purity: SDS-PAGE
CAT. / P2HI0041S / P2HI0041L
KeyTec® MLL1/WDR5/ASH2L/RBBP5/DYP30, N-His/ N-His/N-His/N-GST/N-His
KeyTec® MLL1/WDR5/ASH2L/RBBP5/DYP30, N-His/ N-His/N-His/N-GST/N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His/ N-terminal His/N-terminal His/N-terminal GST/N-terminal His; Sequence: G3762-N3969/M1-C334(end)/M1-P534(end)/M1-L538(end)/ M1-N99(end); Purity: SDS-PAGE
CAT. / P2HE0051S / P2HE0051L
KeyTec® Biotin-PRMT5/MEP50, N-Flag-Avi;N-His
KeyTec® Biotin-PRMT5/MEP50, N-Flag-Avi;N-His
Species: Human; Expression Host: Insect(Sf9); Tag: N-terminal Flag-Avi/N-terminal His; Sequence: A2-L637(end)/R2-E342(end); Purity: SDS-PAGE
CAT. / P2HI0053S / P2HI0053L
KeyTec® PRMT8, N-His
KeyTec® PRMT8, N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: M61-R394; Purity: SDS-PAGE
CAT. / P2HE0049S / P2HE0049L
KeyTec® SETD7, N-His
KeyTec® SETD7, N-His
Species: Human; Expression Host: E.coli; Tag: N-terminal His; Sequence: Y110-K366; Purity: SDS-PAGE
CAT. / P2HE0039S / P2HE0039L
KeyTec® BRD2(BD1/BD2), N-GST
KeyTec® BRD2(BD1/BD2), N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST tag; Sequence: E65-E459; Purity: SDS-PAGE; Application: TR-FRET; Activity: Binding activity
CAT. / P2HE0054S / P2HE0054L
KeyTec® BRD4(BD2), N-GST
KeyTec® BRD4(BD2), N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST tag; Sequence: P342-E460; Purity: SDS-PAGE; Application: TR-FRET; Activity: Binding activity
CAT. / P2HE0055S / P2HE0055L
KeyTec® BRD4(BD1), N-GST
KeyTec® BRD4(BD1), N-GST
Species: Human; Expression Host: E.coli; Tag: N-terminal GST tag; Sequence: E49-E170; Purity: SDS-PAGE; Application: TR-FRET; Activity: Binding activity
CAT. / P2HE0056S / P2HE0056L

Outstanding Features

Strict Quality Control
Strict Quality Control

A strict QC (quality control) test report is provided for each batch.

Good Enzyme Activity
Good Enzyme Activity

Each batch has been verified for enzyme activity. 

Suitable for High-Throughput Screening
Suitable for High-Throughput Screening

Verified by common homogeneous methods such as TR-FRET, Luminescence and fluorescence. 

Cost-Effective
Cost-Effective

High-performance at competitive prices.

Product Competitiveness

Product Competitiveness

For KeyTec® protein products, each batch of protein is subjected to a series of rigorous validation procedures to obtain data such as purity, monomer/polymer morphology, enzyme activity information, positive compound validation information, and so forth.